Package: LTFHPlus Type: Package Title: Implementation of LT-FH++ Version: 2.2.0 Authors@R: c( person("Emil Michael", "Pedersen", email = "emp@ph.au.dk", role = c("aut", "cre")), person("Florian", "Privé", email = "florian.prive.21@gmail.com", role = c("aut", "ths")), person("Bjarni Jóhann", "Vilhjálmsson", email = "bjv@econ.au.dk", role = "ths"), person("Esben", "Agerbo", email = "ea@econ.au.dk", role = "ths"), person("Jette", "Steinbach", , "jst@econ.au.dk", role = "aut"), person("Lucas", "Rasmussen", email = "lar.ncrr@au.dk", role = "ctb")) Description: Implementation of LT-FH++, an extension of the liability threshold family history (LT-FH) model. LT-FH++ uses a Gibbs sampler for sampling from the truncated multivariate normal distribution and allows for flexible family structures. LT-FH++ was first described in Pedersen, Emil M., et al. (2022) as an extension to LT-FH with more flexible family structures, and again as the age-dependent liability threshold (ADuLT) model Pedersen, Emil M., et al. (2023) as an alternative to traditional time-to-event genome-wide association studies, where family history was not considered. License: GPL-3 Imports: batchmeans, dplyr, future.apply, future, purrr, Rcpp, rlang, stats, stringr, tibble, tmvtnorm, tidyselect, igraph, xgboost, tidyr, ggplot2 Suggests: MASS, knitr, rmarkdown, kinship2, testthat LinkingTo: Rcpp Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Language: en-GB URL: https://emilmip.github.io/LTFHPlus/, https://github.com/EmilMiP/LTFHPlus BugReports: https://github.com/EmilMiP/LTFHPlus/issues Config/pak/sysreqs: libglpk-dev make libicu-dev libxml2-dev Repository: https://emilmip.r-universe.dev Date/Publication: 2025-11-17 09:40:32 UTC RemoteUrl: https://github.com/emilmip/ltfhplus RemoteRef: HEAD RemoteSha: 958e8a6817c14a6f1f34c451f5aa89e14a63b262 NeedsCompilation: yes Packaged: 2026-10-14 07:20:04 UTC; root Author: Emil Michael Pedersen [aut, cre], Florian Privé [aut, ths], Bjarni Jóhann Vilhjálmsson [ths], Esben Agerbo [ths], Jette Steinbach [aut], Lucas Rasmussen [ctb] Maintainer: Emil Michael Pedersen