LTFHPlus - Implementation of LT-FH++
Implementation of LT-FH++, an extension of the liability
threshold family history (LT-FH) model. LT-FH++ uses a Gibbs
sampler for sampling from the truncated multivariate normal
distribution and allows for flexible family structures. LT-FH++
was first described in Pedersen, Emil M., et al. (2022)
<https://pure.au.dk/ws/portalfiles/portal/353346245/> as an
extension to LT-FH with more flexible family structures, and
again as the age-dependent liability threshold (ADuLT) model
Pedersen, Emil M., et al. (2023)
<https://www.nature.com/articles/s41467-023-41210-z> as an
alternative to traditional time-to-event genome-wide
association studies, where family history was not considered.